Catnip Herb – Some Useful Advanced Information
What Is Catnip?
Catnip Herb – Some Useful Advanced Information: This plant's scientific name is Nepeta cataria L. Catmint is one of the most prevalent names for catnip.
Catnip, a perennial herb native to Europe, has spread to the northeastern United States and Canada. The plant grows to about 1 m in height and has dark green, oval-toothed leaves. The plant's therapeutic benefits are found in its dried leaves and white blossoming tips.
This term's scientific name (s)
Nepeta cataria L. is a plant in the Lamiaceae family (mint family)
Noun Form (s).
There are several other names for catnip, including cat herb, catnip, and catnip.
An ethnobotanical application.
They can be used as a flavouring ingredient in a wide range of cuisines, from soup to stew to various patent beverages and fruit-based liqueurs. The first proof can be found in 1735. It has been stated that catnip leaves and flowers are used in herbal cocktails.
The herb was also used to treat gastrointestinal spasms and indigestion as a diaphoretic, sedative, and hunger stimulant. In addition to diarrhoea and colic, the herb has been used to cure colds and even cancer.
Catnip tea was traditionally used to treat uneasiness, stomach issues, rashes, and colds in Appalachia. To treat respiratory ailments, dried leaves were smoked and a poultice was applied to the affected area.
In the early 1900s, flowers and leaves were used to postpone menstruation. Catnip was smoked in the 1960s because of its euphoric effects, according to mythology.
Catnip has been reported to contain around 20 distinct compounds, the concentration of which varies dramatically according on the blooming season and location.
The plant contains various sesquiterpenes and monoterpenes, and nepetalactone and beta-caryophyllenes have been discovered using gas chromatography and nuclear magnetic resonance spectroscopy.
Nepetalactone, like valerian's valepotriates, may have an important cat-suppressive action. The majority of the important components in catnip essential oil have been identified as citronellyl acetate and citronellol.
It also contains camphor and thymol, as well as other chemicals including carvacrol and nerol.
Acute and repeated treatment of apolar or polar catnip extracts (48 mg/kg/day) for seven days showed antidepressant, antianxiety, and motor benefits in mice, according to studies. A well-balanced diet reduced the amount of time a patient remained immobile.
These findings were analogous to those obtained in mice treated with the antidepressant fluoxetine; in the outside test, the apolar extract reduced locomotor activity, rising frequency, and immobility duration.
The behavioural despair test revealed that mice given the apoland extract had a shorter immobility period. Furthermore, the apolar extract shortened the time it needed for the first immobilisation.
According to the study's findings, a catnip-enriched diet and apolar extract may have antidepressant properties. Male rats fed diets enriched with 10% N. cataria leaves for four hours showed antidepressant effects.
In vitro testing
In an in vitro study, flavonoids extracted from N. cataria L. were used to treat the A549 non-small cell lung cancer cell line.
The anticancer impact increased due to increasing apoptosis and necrosis rates in A549 cells as flavonoid concentration increased. VEGFR and PI3K mRNA levels in A549 cells were lowered in the treatment group, but PTEN levels increased.
AKT, cyclin B1, and Bcl-2 levels decreased as PI3K protein levels increased. According to these findings, flavonoid extracts from N. cataria L. may prevent lung cancer through affecting the PTEN/PI3K/AKT pathway.
Insect repellent spray
Animal and in vitro research
Catnip nepetalactone and iridoids have been studied for their insecticide and herbicide capabilities. Catnip oil has been tested in the field in the United States for its capacity to repel mosquitoes, black flies, stable flies, and deer ticks (Bernier 2005, Feaster 2009). The attraction inhibition of diethyltoluamide is greater (DEET).
Catnip oil components were more effective in vitro than a control at repelling yellow fever mosquitoes (Aedes aegypti L.). When it came to Chauhan in 2005, houseflies, stable flies, and filth flies were efficiently repelled at doses of 2 mg and 20 mg of catnip.
Zhu is the owner of the year 2009. Catnip oil-treated filter paper and wax-based catnip pellets (32 mg per pellet) applied to waste areas of cow pastures both repelled houseflies. Zhu (2010), p. Another study used three different doses of catnip oil to assess its repellent effect on predators (0.2, 2 and 20 mg).
Catnip oil was found to be more effective than DEET at repelling stable insects from a person's body, with the most significant amount providing the best protection. Only a few eggs were laid on cloths treated with 100 mg catnip oil for six hours, indicating an egg-laying deterrent effect.
In the study's field testing, catnip oil concentrations of 15% and 30% were used to repel stable flies. The capacity of fly oviposition to persist in oviposition cups was shown to be substantially decreased by 500 mg of encapsulated catnip oil.
Catnip oil capsules reduced the quantity of eggs laid on stable flies' larval substrate by 85% and more than 98%, respectively. Zhu's year had arrived. In a lab environment, a 20 mg catnip oil dosage repelled horn flies for six hours. Cattle effectively repelled horn flies when treated with 15% catnip oil.
Rabbits were fed catnip N. cataria (CNC) and Rhizoma coptidis (RC) orally. CNC absorbed and released berberine, an alkaloid found in Rhizoma coptidis, more easily. The bioavailability of coptisine, palmatine, and epiberberine was lowered. CNC may also lower Epiberberine levels in the blood.
Because CNC micro particles can adsorb alkaloids and extend their retention in the small intestine, different alkaloids may have different effects.
Within 24 hours of using 0.1 ml catnip oil, the conjunctiva on the upper and lower eyelids got inflamed. Rabbits were also given 0.5 mL of undiluted catnip oil for 14 days of research. From day 3 to day 4, all animals developed redness during the evaluation period.
According to a recent study, the lethal dose of catnip oil is 1,300 mg/kg intraperitoneally.
In 2002, Duke University Catnip abuse did not frequently result in significant bodily consequences.
However, mild symptoms such as a headache and fatigue have been reported. If a big amount of tea is taken in excess, it may produce vomiting.
A study that covered acute oral and dermal toxicities as well as primary sensitization looked at the effects of toxins on the skin, eyes, and dermis in mice, rats, and rabbits. For 14 days, a daily dose of 1,000 to 10,000 mg/kg catnip oil was administered orally. There were no toxicities at dosages ranging from 1,000 to 2,150 mg/kg, with the exception of one fatality.
A dose of 4,640 mg/kg or above resulted in a 100% fatality rate. Acute inhalation tests in mice exposed for 2 hours, topical research in which 5,000 mg/kg was applied to the shaved back of rats, and Catnip oil applied to the upper and lower eyelids of rabbits for 14 days had no negative influence on the animals' eyes.
Data on Species
N. cataria leaf supplementation in male rats' meals for four hours improved their sexual behaviour and performance, as demonstrated by a decrease in ascents preceding ejaculatory ascents and an increase in the frequency of apomorphine-induced penile erections. N. cataria improves apomorphine-induced penile erection, indicating that the active ingredients contain dopaminergic characteristics.
A wide range of applications
The use of catnip as a human pesticide is the only clinical evidence to support its use in humans.
How much should I drink?
The therapeutic dose of catnip has never been studied. A normal sedative dosage is 4 grammes of the dried plant, which is typically consumed as a tea. An insect repellent cream with 15% essential oil was used.